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Histone H1(AE-4), CF405S conjugate, 0.1mg/mL [26628-22-8]

Histone H1(AE-4), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC040096
Biotium
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse, Rat
TargetH1-0
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Overview

  • Supplier
    Biotium
  • Product Name
    Histone H1(AE-4), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    AE-4
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID3005
  • Target name
    H1-0
  • Target description
    H1.0 linker histone
  • Target synonyms
    H1 histone family member 0; H1.0; H1.0, H1(0), H1-0; H10; H1F0; H1FV; histone H1'; histone H1(0); histone H1.0
  • Host
    Mouse
  • Isotype
    IgG2a
  • Scientific Description
    Eukaryotic histones are basic, water-soluble nuclear proteins that form hetero-octameric nucleosome particles. They wrap 146 base pairs of DNA in a left-handed supealpha-helicalturn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203