Histone H2A.Z (Acetyl Lys4) antibody [RM221]

GeneTex

Histone H2A.Z (Acetyl Lys4) antibody [RM221] - Orthogonal Validated

9

This antibody reacts to Histone H2A.Z acetylated at Lysine 4 (K4ac). No cross reactivity with non-modified Lysine 4 or other acetylated Lysines in histone H2A

WB: 0.5 microg/mL - 2 microg/mL. ICC/IF: 1 microg/mL - 2 microg/mL. ELISA: 0.2 microg/mL - 1 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Monoclonal

RM221

Unconjugated

H2AZ1

H2A.Z variant histone 1

H2A histone family member Z; H2A.z; H2A.Z-1; H2A/z; H2AFZ; H2AZ; H2AZ histone; histone H2A.Z

Rabbit

IgG

Histone H2A.Z

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203