IHC-P analysis of human placenta (amnion and chorion) tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX?. Strong nuclear HMGB1 staining of chorion cells and moderate nuclear HMGB1 staining of amnion cells.
![IHC-P analysis of human esophageal squamous cell carcinoma (ESCC) tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX?. Squamous cell carcinoma with strong HMGB1 staining of tumor cells.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639941/GTX639941_20240514_IHC-P_1_24051319_568.webp "IHC-P analysis of human esophageal squamous cell carcinoma (ESCC) tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX?. Squamous cell carcinoma with strong HMGB1 staining of tumor cells.")
![IHC-P analysis of human primitive neuroektodermal tumor (PNET) from soft tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX?. Primitive neuroektodermal tumor (PNET) showing intense HMGB1 staining of tumor cells.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639941/GTX639941_20240514_IHC-P_2_24051319_394.webp "IHC-P analysis of human primitive neuroektodermal tumor (PNET) from soft tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX?. Primitive neuroektodermal tumor (PNET) showing intense HMGB1 staining of tumor cells.")
![IHC-P analysis of human ovarian clear cell carcinoma (OCCC) tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX?. A complete lack of HMGB1 staining in tumor cells.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639941/GTX639941_20250214_IHC-P_1_25021323_702.webp "IHC-P analysis of human ovarian clear cell carcinoma (OCCC) tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX?. A complete lack of HMGB1 staining in tumor cells.")
![IHC-P analysis of human testis tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX?. A continuous decrease of HMGB1 staining during maturation of germ cells. Spermatocytes and spermatids are largely HMGB1 negative.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639941/GTX639941_20250214_IHC-P_2_25021323_527.webp "IHC-P analysis of human testis tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX?. A continuous decrease of HMGB1 staining during maturation of germ cells. Spermatocytes and spermatids are largely HMGB1 negative.")
![IHC-P analysis of human muscle-invasive urothelial carcinoma tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX?. A strong HMGB1 positivity of all tumor cells (Startbild).](https://www.genetex.com/upload/website/prouct_img/normal/GTX639941/GTX639941_20250214_IHC-P_25021323_632.webp "IHC-P analysis of human muscle-invasive urothelial carcinoma tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX?. A strong HMGB1 positivity of all tumor cells (Startbild).")
IHC-P analysis of human placenta (amnion and chorion) tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX?. Strong nuclear HMGB1 staining of chorion cells and moderate nuclear HMGB1 staining of amnion cells.
HMGB1 antibody [HMV317] HistoMAX(tm)
GTX639941
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetHMGB1
Overview
- SupplierGeneTex
- Product NameHMGB1 antibody [HMV317] HistoMAX(tm)
- Delivery Days Customer7
- Application Supplier NoteIHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHMV317
- Concentration33 ug/ml
- ConjugateUnconjugated
- Gene ID3146
- Target nameHMGB1
- Target descriptionhigh mobility group box 1
- Target synonymsHMG-1, HMG1, HMG3, SBP-1, high mobility group protein B1, Amphoterin, Sulfoglucuronyl carbohydrate binding protein, high-mobility group (nonhistone chromosomal) protein 1
- HostRabbit
- IsotypeIgG
- Protein IDP09429
- Protein NameHigh mobility group protein B1
- Scientific DescriptionThis gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
Datasheet
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