Hsp90 beta antibody
GTX101448
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetHSP90AB1
Overview
- SupplierGeneTex
- Product NameHsp90 beta antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID3326
- Target nameHSP90AB1
- Target descriptionheat shock protein 90 alpha family class B member 1
- Target synonymsD6S182; heat shock 84 kDa; heat shock 90kD protein 1, beta; heat shock protein 90 kDa; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein 90kDa alpha family class B member 1; heat shock protein HSP 90-beta; HSP84; HSP90B; HSP90-beta; HSPC2; HSPCB
- HostRabbit
- IsotypeIgG
- Protein IDP08238
- Protein NameHeat shock protein HSP 90-beta
- Scientific DescriptionHSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM]
- ReactivityHuman, Mouse, Rat, Zebra Fish
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Cardiac myofibrillogenesis is spatiotemporally modulated by the molecular chaperone UNC45B.Read more
- Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality.Read more
- Adult fibroblasts use aggresomes only in distinct cell-states.Read more
- Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality. Navare AT et al., 2020 Nov 6, bioRxivRead more
- Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer. Ono K et al., 2020 May 31, J Extracell VesiclesRead more
- Multiexon deletion alleles of ATF6 linked to achromatopsia. Lee EJ et al., 2020 Apr 9, JCI InsightRead more
- Cell Stress Induced Stressome Release Including Damaged Membrane Vesicles and Extracellular HSP90 by Prostate Cancer Cells. Eguchi T et al., 2020 Mar 19, CellsRead more
- Carcinogenic epithelial-mesenchymal transition initiated by oral cancer exosomes is inhibited by anti-EGFR antibody cetuximab. Fujiwara T et al., 2018 Nov, Oral OncolRead more
- Genomic analysis of DNA repair genes and androgen signaling in prostate cancer. Jividen K et al., 2018 Oct 10, BMC CancerRead more
- Anti-EGFR antibody cetuximab is secreted by oral squamous cell carcinoma and alters EGF-driven mesenchymal transition. Fujiwara T et al., 2018 Sep 10, Biochem Biophys Res CommunRead more