HTR1A Antibody, FITC conjugated
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CSB-PA010881LC01HU
ReactivityHuman
Product group Antibodies
TargetHTR1A
Overview
- SupplierCusabio
- Product NameHTR1A Antibody, FITC conjugated
- Delivery Days Customer20
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateFITC
- FormulationLiquid
- Gene ID3350
- Target nameHTR1A
- Target description5-hydroxytryptamine receptor 1A
- Target synonyms5HT1a; 5-HT1A; 5-HT-1A; 5-HT1a receptor; 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled; 5-hydroxytryptamine receptor 1A; ADRB2RL1; ADRBRL1; G-21; guanine nucleotide-binding regulatory protein-coupled receptor; PFMCD
- HostRabbit
- IsotypeIgG
- Scientific DescriptionG-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203