IGF1R alpha + beta antibody [alphaIR3]

GeneTex

IGF1R antibody [alphaIR3]

9

This antibody recognizes the ~130 kDa α and the ~90 kDa β subunits of IGF-I receptor and is not suitable for use in IHC-P or WB.

ICC/IF: 1 - 5 microg/ml. Neutralizing/Inhibition: 1 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, Neutralisation/Blocking

Research Use Only

Monoclonal

alphaIR3

0.1 mg/ml

Unconjugated

IGF1R

insulin like growth factor 1 receptor

CD221; IGF-I receptor; IGFIR; IGFR; insulin-like growth factor 1 receptor; JTK13; soluble IGF1R variant 1; soluble IGF1R variant 2

Mouse

IgG1

Insulin-like growth factor 1 receptor

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Human

2°C to 8°C

12352203