IL23 antibody

GeneTex

IL23 antibody

9

This antibody is specific for IL-23 N-Terminus

WB: 1 - 2 microg/mL. IHC-P: 2 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

1 mg/ml

Liquid

IL23A

interleukin 23 subunit alpha

IL-23; IL-23 subunit alpha; IL-23A; IL-23-A; IL23P19; IL-23p19; interleukin 23 p19 subunit; interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; P19; SGRF

Interleukin-23 subunit alpha

Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes (3,4). Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.

-20°C or -80°C,2°C to 8°C

12352203