![GTX100789 WB Image GTX100789 WB Image](https://www.genetex.com/upload/website/prouct_img/normal/GTX100789/GTX100789_39911_20190118_WB_Fraction_19022001_394.jpg)
GTX100789 WB Image
Integrin alpha V antibody [C2C3], C-term
![Research Use Only](static/images/certificates/ruo.jpg)
GTX100789
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameIntegrin alpha V antibody [C2C3], C-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.58 mg/ml
- IsotypeIgG
- Scientific DescriptionITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; ITGB1, ITGB3, ITGB5, ITGB6, and ITGB8), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A small physiological electric field mediated responses of extravillous trophoblasts derived from HTR8/SVneo cells: involvement of activation of focal adhesion kinase signaling. Zhang J et al., 2014, PLoS OneRead more
- Adhesive and migratory effects of phosphophoryn are modulated by flanking peptides of the integrin binding motif. Suzuki S et al., 2014, PLoS OneRead more
- Large-Scale Proteomic Identification of Targets of Cellular miR-197 Downregulated by Enterovirus A71. Tang WF et al., 2019 Jan 4, J Proteome ResRead more
- The role of integrin alphav in proliferation and differentiation of human dental pulp cell response to calcium silicate cement. Hung CJ et al., 2014 Nov, J EndodRead more