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ProductsBack/Integrin alpha V antibody [C2C3], C-term

Integrin alpha V antibody [C2C3], C-term

GTX100789
GeneTex
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetITGAV
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Overview

  • Supplier
    GeneTex
  • Product Name
    Integrin alpha V antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.41 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3685
  • Target name
    ITGAV
  • Target description
    integrin subunit alpha V
  • Target synonyms
    CD51, MSK8, VNRA, VTNR, integrin alpha-V, antigen identified by monoclonal antibody L230, integrin alphaVbeta3, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), vitronectin receptor subunit alpha
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP06756
  • Protein Name
    Integrin alpha-V
  • Scientific Description
    ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; ITGB1, ITGB3, ITGB5, ITGB6, and ITGB8), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Tang WF, Huang RT, Chien KY, et al. Large-Scale Proteomic Identification of Targets of Cellular miR-197 Downregulated by Enterovirus A71. J Proteome Res. 2019,18(1):449-460. doi: 10.1021/acs.jproteome.8b00762
    Read this paper
  • Suzuki S, Kobuke S, Haruyama N, et al. Adhesive and migratory effects of phosphophoryn are modulated by flanking peptides of the integrin binding motif. PLoS One. 2014,9(11):e112490. doi: 10.1371/journal.pone.0112490
    Read this paper
  • Hung CJ, Hsu HI, Lin CC, et al. The role of integrin αv in proliferation and differentiation of human dental pulp cell response to calcium silicate cement. J Endod. 2014,40(11):1802-9. doi: 10.1016/j.joen.2014.07.016
    Read this paper
  • Zhang J, Ren R, Luo X, et al. A small physiological electric field mediated responses of extravillous trophoblasts derived from HTR8/SVneo cells: involvement of activation of focal adhesion kinase signaling. PLoS One. 2014,9(3):e92252. doi: 10.1371/journal.pone.0092252
    Read this paper

Datasheet

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