ProductsBack/Involucrin antibody [N1N2], N-term

Involucrin antibody [N1N2], N-term

Name: Involucrin antibody [N1N2], N-term
SKU: GTX116012_G10
Availability: BackOrder

GTX116012

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetIVL

Overview

Supplier
GeneTex
Product Name
Involucrin antibody [N1N2], N-term
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.72 mg/ml
Conjugate
Unconjugated
Gene ID3713
Target name
IVL
Target description
involucrin
Target synonyms
involucrin
Host
Rabbit
Isotype
IgG
Protein IDP07476
Protein Name
Involucrin
Scientific Description
Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Colombo I, Sangiovanni E, Maggio R, et al. HaCaT Cells as a Reliable In Vitro Differentiation Model to Dissect the Inflammatory/Repair Response of Human Keratinocytes. Mediators Inflamm. 2017,2017:7435621. doi: 10.1155/2017/7435621
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Qian L, Xu F, Wang X, et al. LncRNA expression profile of ΔNp63α in cervical squamous cancers and its suppressive effects on LIF expression. Cytokine. 2017,96:114-122. doi: 10.1016/j.cyto.2017.04.001
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Dang NN, Pang SG, Song HY, et al. Filaggrin silencing by shRNA directly impairs the skin barrier function of normal human epidermal keratinocytes and then induces an immune response. Braz J Med Biol Res. 2015,48(1):39-45.
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Dang N, Pang S, Song H, et al. Knockdown of filaggrin influences the epidermal terminal differentiation via MAPK pathway in normal human epidermal keratinocytes. Mol Biol Rep. 2015,42(2):337-43. doi: 10.1007/s11033-014-3765-6
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Igawa K, Kokubu C, Yusa K, et al. Removal of reprogramming transgenes improves the tissue reconstitution potential of keratinocytes generated from human induced pluripotent stem cells. Stem Cells Transl Med. 2014,3(9):992-1001. doi: 10.5966/sctm.2013-0179
Read this paper