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ProductsBack/Involucrin antibody [N1N2], N-term

Involucrin antibody [N1N2], N-term

Research Use Only
GTX116012
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetIVL
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Overview

  • Supplier
    GeneTex
  • Product Name
    Involucrin antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.72 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID3713
  • Target name
    IVL
  • Target description
    involucrin
  • Target synonyms
    involucrin
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP07476
  • Protein Name
    Involucrin
  • Scientific Description
    Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • HaCaT Cells as a Reliable In Vitro Differentiation Model to Dissect the Inflammatory/Repair Response of Human Keratinocytes. Colombo I et al., 2017, Mediators Inflamm
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  • LncRNA expression profile of deltaNp63alpha in cervical squamous cancers and its suppressive effects on LIF expression. Qian L et al., 2017 Aug, Cytokine
    Read more
  • Filaggrin silencing by shRNA directly impairs the skin barrier function of normal human epidermal keratinocytes and then induces an immune response. Dang NN et al., 2015 Jan, Braz J Med Biol Res
    Read more
  • Knockdown of filaggrin influences the epidermal terminal differentiation via MAPK pathway in normal human epidermal keratinocytes. Dang N et al., 2015 Feb, Mol Biol Rep
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  • Removal of reprogramming transgenes improves the tissue reconstitution potential of keratinocytes generated from human induced pluripotent stem cells. Igawa K et al., 2014 Sep, Stem Cells Transl Med
    Read more