IHC-P analysis of human tonsil tissue using GTX34804 Involucrin antibody [SY5].
IHC-P analysis of human tonsil tissue using GTX34804 Involucrin antibody [SY5].
Involucrin antibody [SY5]
GTX34804
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Human, Monkey, Porcine, Primate
TargetIVL
Overview
- SupplierGeneTex
- Product NameInvolucrin antibody [SY5]
- Delivery Days Customer9
- Antibody SpecificityIt recognizes a protein of 66kDa-170kDa, identified as involucrin. In Western blotting of cultured human keratinocytes, this MAb reacts with a 120kDa protein. It stains the involucrin in a variety of sizes: 170kDa in MCF-7 cells, a doublet of ~115kDa and
- Application Supplier NoteIHC-P: 0.1-0.2microg/ml for 30 min at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSY5
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID3713
- Target nameIVL
- Target descriptioninvolucrin
- Target synonymsinvolucrin
- HostMouse
- IsotypeIgG1
- Protein IDP07476
- Protein NameInvolucrin
- Scientific DescriptionInvolucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008]
- ReactivityCanine, Human, Monkey, Porcine, Primate
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Rho kinase inhibitor Y-27632 promotes the differentiation of human bone marrow mesenchymal stem cells into keratinocyte-like cells in xeno-free conditioned medium. Li Z et al., 2015 Mar 11, Stem Cell Res TherRead more
- Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities. Suarez-Farinas M et al., 2011 Apr, J Allergy Clin ImmunolRead more
- Human eccrine sweat gland cells can reconstitute a stratified epidermis. Biedermann T et al., 2010 Aug, J Invest DermatolRead more