IHC-P analysis of human tonsil tissue using GTX01894 IRF4 / MUM1 antibody [EAU32]. Note nuclear staining of B cells showing lymphoplasmacytic differentiation.
IHC-P analysis of human tonsil tissue using GTX01894 IRF4 / MUM1 antibody [EAU32]. Note nuclear staining of B cells showing lymphoplasmacytic differentiation.
IRF4 / MUM1 antibody [EAU32]
GTX01894
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetIRF4
Overview
- SupplierGeneTex
- Product NameIRF4 / MUM1 antibody [EAU32]
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDEAU32
- ConjugateUnconjugated
- Gene ID3662
- Target nameIRF4
- Target descriptioninterferon regulatory factor 4
- Target synonymsinterferon regulatory factor 4; LSIRF; lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; SHEP8
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203