IRF4 / MUM1 antibody

GeneTex

IRF4 / MUM1 antibody

9

IRF4 / MUM1 antibody is predicted to not cross-react with other IRF protein family members. IRF4 / MUM1 often migrates at a higher than predicted molecular weight in SDS-PAGE.

WB: 0.5 microg/mL. ICC/IF: 10 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

IRF4

interferon regulatory factor 4

interferon regulatory factor 4; LSIRF; lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; SHEP8

Rabbit

IgG

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]

Human, Mouse, Rat

2°C to 8°C

12352203