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ELISA analysis of antigen using GTX60660 KEAP1 antibody [1F10B6]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng
ELISA analysis of antigen using GTX60660 KEAP1 antibody [1F10B6]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng
ELISA analysis of antigen using GTX60660 KEAP1 antibody [1F10B6]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng

KEAP1 antibody [1F10B6]

GTX60660
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetKEAP1
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Overview

  • Supplier
    GeneTex
  • Product Name
    KEAP1 antibody [1F10B6]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1/500 - 1/2000. ICC/IF: 1/50. FACS: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1F10B6
  • Conjugate
    Unconjugated
  • Gene ID9817
  • Target name
    KEAP1
  • Target description
    kelch like ECH associated protein 1
  • Target synonyms
    INrf2, KLHL19, kelch-like ECH-associated protein 1, KEAP1 delta C, cytosolic inhibitor of Nrf2, kelch-like family member 19, kelch-like protein 19
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ14145
  • Protein Name
    Kelch-like ECH-associated protein 1
  • Scientific Description
    This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Arellano Buendia AS, Juárez Rojas JG, García-Arroyo F, et al. Antioxidant and anti-inflammatory effects of allicin in the kidney of an experimental model of metabolic syndrome. PeerJ. 2023,11:e16132. doi: 10.7717/peerj.16132
    Read this paper
  • Sánchez-Gloria JL, Martínez-Olivares CE, Del Valle-Mondragón L, et al. Allicin, an Emerging Treatment for Pulmonary Arterial Hypertension: An Experimental Study. Int J Mol Sci. 2023,24(16). doi: 10.3390/ijms241612959
    Read this paper
  • Li L, Xuan Y, Zhu B, et al. Protective Effects of Cannabidiol on Chemotherapy-Induced Oral Mucositis via the Nrf2/Keap1/ARE Signaling Pathways. Oxid Med Cell Longev. 2022,2022:4619760. doi: 10.1155/2022/4619760
    Read this paper
  • Xia L, Gong M, Zou Y, et al. Apatinib Induces Ferroptosis of Glioma Cells through Modulation of the VEGFR2/Nrf2 Pathway. Oxid Med Cell Longev. 2022,2022:9925919. doi: 10.1155/2022/9925919
    Read this paper
  • Arellano-Buendía AS, Castañeda-Lara LG, Loredo-Mendoza ML, et al. Effects of Allicin on Pathophysiological Mechanisms during the Progression of Nephropathy Associated to Diabetes. Antioxidants (Basel). 2020,9(11). doi: 10.3390/antiox9111134
    Read this paper
  • Hsieh YH, Deng JS, Chang YS, et al. Ginsenoside Rh2 Ameliorates Lipopolysaccharide-Induced Acute Lung Injury by Regulating the TLR4/PI3K/Akt/mTOR, Raf-1/MEK/ERK, and Keap1/Nrf2/HO-1 Signaling Pathways in Mice. Nutrients. 2018,10(9). doi: 10.3390/nu10091208
    Read this paper
  • García Trejo EMÁ, Arellano Buendía AS, Sánchez Reyes O, et al. The Beneficial Effects of Allicin in Chronic Kidney Disease Are Comparable to Losartan. Int J Mol Sci. 2017,18(9). doi: 10.3390/ijms18091980
    Read this paper