Bio-Connect

KLF5 antibody

GTX103289
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetKLF5
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Overview

  • Supplier
    GeneTex
  • Product Name
    KLF5 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID688
  • Target name
    KLF5
  • Target description
    Kruppel like factor 5
  • Target synonyms
    (intestinal Kruppel-like factor; basic transcription element binding protein 2; BTEB2; BTE-binding protein 2; CKLF; colon krueppel-like factor; colon kruppel-like factor; epididymis secretory sperm binding protein; GC box binding protein 2; IKLF; intestinal-enriched krueppel-like factor; intestinal-enriched kruppel-like factor; Krueppel-like factor 5; Kruppel-like factor 5 (intestinal); transcription factor BTEB2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13887
  • Protein Name
    Krueppel-like factor 5
  • Scientific Description
    This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate. Nagy A et al., 2021 Aug 26, Int J Mol Sci
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  • KLF5-mediated Eppk1 expression promotes cell proliferation in cervical cancer via the p38 signaling pathway. Ma D et al., 2021 Apr 8, BMC Cancer
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  • Vascular Smooth Muscle FTO Promotes Aortic Dissecting Aneurysms via m6A Modification of Klf5. Ma D et al., 2020, Front Cardiovasc Med
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  • Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission. Ma D et al., 2020 Aug, PLoS Biol
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  • Increased AT2R expression is induced by AT1R autoantibody via two axes, Klf-5/IRF-1 and circErbB4/miR-29a-5p, to promote VSMC migration. Sun Y et al., 2020 Jun 8, Cell Death Dis
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  • Krueppel Like Factors Family Expression in Cervical Cancer Cells. Marrero-Rodriguez D et al., 2017 May, Arch Med Res
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  • KLF5 promotes cervical cancer proliferation, migration and invasion in a manner partly dependent on TNFRSF11a expression. Ma D et al., 2017 Nov 16, Sci Rep
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  • Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming. Miura S et al., 2017 Oct 5, Cell Stem Cell
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  • iNOS-derived peroxynitrite mediates high glucose-induced inflammatory gene expression in vascular smooth muscle cells through promoting KLF5 expression and nitration. Zhang ML et al., 2017 Nov, Biochim Biophys Acta Mol Basis Dis
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  • Tongxinluo inhibits neointimal formation by regulating the expression and post-translational modification of KLF5 in macrophages. Jiang W et al., 2016, Am J Transl Res
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