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KLF5 antibody

GTX103289
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetKLF5
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Overview

  • Supplier
    GeneTex
  • Product Name
    KLF5 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID688
  • Target name
    KLF5
  • Target description
    KLF transcription factor 5
  • Target synonyms
    BTEB2, CKLF, IKLF, Krueppel-like factor 5, (intestinal Kruppel-like factor, BTE-binding protein 2, GC box binding protein 2, Kruppel like factor 5, Kruppel-like factor 5 (intestinal), basic transcription element binding protein 2, colon krueppel-like factor, colon kruppel-like factor, epididymis secretory sperm binding protein, intestinal-enriched krueppel-like factor, intestinal-enriched kruppel-like factor, transcription factor BTEB2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13887
  • Protein Name
    Krueppel-like factor 5
  • Scientific Description
    This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Nagy A, Pethő D, Gesztelyi R, et al. BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate. Int J Mol Sci. 2021,22(17). doi: 10.3390/ijms22179263
    Read this paper
  • Ma D, Pan Z, Chang Q, et al. KLF5-mediated Eppk1 expression promotes cell proliferation in cervical cancer via the p38 signaling pathway. BMC Cancer. 2021,21(1):377. doi: 10.1186/s12885-021-08040-y
    Read this paper
  • Ma D, Liu X, Zhang JJ, et al. Vascular Smooth Muscle FTO Promotes Aortic Dissecting Aneurysms via m6A Modification of Klf5. Front Cardiovasc Med. 2020,7:592550. doi: 10.3389/fcvm.2020.592550
    Read this paper
  • Ma D, Zheng B, Liu HL, et al. Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission. PLoS Biol. 2020,18(8):e3000808. doi: 10.1371/journal.pbio.3000808
    Read this paper
  • Sun Y, Li Y, Wang M, et al. Increased AT(2)R expression is induced by AT(1)R autoantibody via two axes, Klf-5/IRF-1 and circErbB4/miR-29a-5p, to promote VSMC migration. Cell Death Dis. 2020,11(6):432. doi: 10.1038/s41419-020-2643-5
    Read this paper
  • Marrero-Rodríguez D, la Cruz HA, Taniguchi-Ponciano K, et al. Krüppel Like Factors Family Expression in Cervical Cancer Cells. Arch Med Res. 2017,48(4):314-322. doi: 10.1016/j.arcmed.2017.06.011
    Read this paper
  • Ma D, Chang LY, Zhao S, et al. KLF5 promotes cervical cancer proliferation, migration and invasion in a manner partly dependent on TNFRSF11a expression. Sci Rep. 2017,7(1):15683. doi: 10.1038/s41598-017-15979-1
    Read this paper
  • Miura S, Suzuki A. Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming. Cell Stem Cell. 2017,21(4):456-471.e5. doi: 10.1016/j.stem.2017.08.020
    Read this paper
  • Zhang ML, Zheng B, Tong F, et al. iNOS-derived peroxynitrite mediates high glucose-induced inflammatory gene expression in vascular smooth muscle cells through promoting KLF5 expression and nitration. Biochim Biophys Acta Mol Basis Dis. 2017,1863(11):2821-2834. doi: 10.1016/j.bbadis.2017.07.004
    Read this paper
  • Jiang W, Zheng B, Zhang XH, et al. Tongxinluo inhibits neointimal formation by regulating the expression and post-translational modification of KLF5 in macrophages. Am J Transl Res. 2016,8(11):4778-4790.
    Read this paper

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