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Latrophilin 1 antibody

Research Use Only
GTX71123
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Hamster, Human, Mammals, Monkey, Mouse, Porcine, Rabbit, Rat
TargetADGRL1

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Overview

  • Supplier
    GeneTex
  • Product Name
    Latrophilin 1 antibody
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.74 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID22859
  • Target name
    ADGRL1
  • Target description
    adhesion G protein-coupled receptor L1
  • Target synonyms
    adhesion G protein-coupled receptor L1; calcium-independent alpha-latrotoxin receptor 1; CIRL1; CIRL-1; CL1; latrophilin-1; LEC2; lectomedin-2; LPHN1
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
  • Reactivity
    Bovine, Canine, Hamster, Human, Mammals, Monkey, Mouse, Porcine, Rabbit, Rat
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203