Latrophilin 1 antibody
GTX71123
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Hamster, Human, Mammals, Monkey, Mouse, Porcine, Rabbit, Rat
TargetADGRL1
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Overview
- SupplierGeneTex
- Product NameLatrophilin 1 antibody
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.74 mg/ml
- ConjugateUnconjugated
- Gene ID22859
- Target nameADGRL1
- Target descriptionadhesion G protein-coupled receptor L1
- Target synonymsadhesion G protein-coupled receptor L1; calcium-independent alpha-latrotoxin receptor 1; CIRL1; CIRL-1; CL1; latrophilin-1; LEC2; lectomedin-2; LPHN1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
- ReactivityBovine, Canine, Hamster, Human, Mammals, Monkey, Mouse, Porcine, Rabbit, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203