Latrophilin 1 antibody

GeneTex

Latrophilin 1 antibody

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.74 mg/ml

Unconjugated

ADGRL1

adhesion G protein-coupled receptor L1

adhesion G protein-coupled receptor L1; calcium-independent alpha-latrotoxin receptor 1; CIRL1; CIRL-1; CL1; latrophilin-1; LEC2; lectomedin-2; LPHN1

Rabbit

IgG

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]

Bovine, Canine, Hamster, Human, Mammals, Monkey, Mouse, Porcine, Rabbit, Rat

2°C to 8°C,-20°C or -80°C

12352203