WB analysis of various samples using GTX28075 Lck antibody [LCK-01]. Lane 1 : J. CaM-1.6 (a mutant derivate of the JURKAT cell line) transfected with Lck Lane 2 : HEK-293T transfected with Lck Lane 3 : HEK-293T (non-transfected)
Lck antibody [LCK-01]
GTX28075
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetLCK
Overview
- SupplierGeneTex
- Product NameLck antibody [LCK-01]
- Delivery Days Customer9
- Antibody SpecificityThis antibody recognizes defined epitope (aa 22-36) of Lck, a 56 kDa Src-family protein tyrosine kinase.,We do not recommend use of this product for Mouse.
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDLCK-01
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3932
- Target nameLCK
- Target descriptionLCK proto-oncogene, Src family tyrosine kinase
- Target synonymsIMD22; leukocyte C-terminal Src kinase; LSK; lymphocyte cell-specific protein-tyrosine kinase; p56(LSTRA) protein-tyrosine kinase; p56lck; pp58lck; proto-oncogene tyrosine-protein kinase LCK; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyrosine-protein kinase Lck; YT16
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203