LEF1 antibody [REMB1]
GTX12034
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetLEF1
Overview
- SupplierGeneTex
- Product NameLEF1 antibody [REMB1]
- Delivery Days Customer9
- Application Supplier NoteWB: 1-5 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDREMB1
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID51176
- Target nameLEF1
- Target descriptionlymphoid enhancer binding factor 1
- Target synonymsLEF-1; lymphoid enhancer-binding factor 1; T cell-specific transcription factor 1-alpha; TCF10; TCF1ALPHA; TCF1-alpha; TCF7L3
- HostMouse
- IsotypeIgG1
- Protein IDQ9UJU2
- Protein NameLymphoid enhancer-binding factor 1
- Scientific DescriptionLymphoid enhancer factor, LEF1, is a transcription factor of the High Mobility Group of DNA binding proteins. It is one member of a family of four proteins referred to as LEF/TCF transcription factors (LEF1, TCF1, TCF3 and TCF4). These factors play crucial roles in WNT/Wingless signaling, a signal transduction cascade that directs cell differentiation. Aberrant activation of the WNT/Wingless pathway is also a root cause in the genesis of certain cancers such as colon cancer, melanoma and breast cancer.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy. Lancaster MA et al., 2009 Sep, Nat MedRead more