LRPPRC Antibody, Biotin conjugated

Cusabio

LRPPRC Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

LRPPRC

leucine rich pentatricopeptide repeat containing

130 kDa leucine-rich protein; CLONE-23970; GP130; leucine-rich PPR motif-containing protein, mitochondrial; leucine-rich PPR-motif containing; LRP 130; LRP130; LSFC; MC4DN5; mitochondrial leucine-rich PPR motif-containing protein

Rabbit

IgG

Leucine-rich PPR motif-containing protein, mitochondrial

May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).

Human

-20°C or -80°C

12352203