
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA618886LA01HU at dilution of 1:100
LRRC32 Antibody
CSB-PA618886LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetLRRC32
Overview
- SupplierCusabio
- Product NameLRRC32 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2615
- Target nameLRRC32
- Target descriptionleucine rich repeat containing 32
- Target synonymsCPPRDD, D11S833E, GARP, transforming growth factor beta activator LRRC32, garpin, glycoprotein A repetitions predominant, leucine-rich repeat-containing protein 32
- HostRabbit
- IsotypeIgG
- Protein IDQ14392
- Protein NameTransforming growth factor beta activator LRRC32
- Scientific DescriptionKey regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19750484, PubMed:19651619, PubMed:22278742). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:22278742). Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta (PubMed:22278742). Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) (PubMed:19750484, PubMed:19651619). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3) (By similarity).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
![WB analysis of GARP antigen and its degradatory products in lysate of human thrombocytes using GTX00516 GARP antibody [GARP5].](https://www.genetex.com/upload/website/prouct_img/normal/GTX00516/GTX00516_20191025_AP_001_52_w_23053121_184.webp)


