LXR alpha antibody [C3], C-term

GeneTex

LXR alpha antibody [C3], C-term

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

NR1H3

nuclear receptor subfamily 1 group H member 3

liver X nuclear receptor alpha variant 1; LXRA; LXR-a; oxysterols receptor LXR-alpha; RLD-1

Rabbit

IgG

Oxysterols receptor LXR-alpha

The liver X receptors, LXRA and LXRB (NR1H2; MIM 600380), form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM]

Human

-20°C or -80°C,2°C to 8°C

12352203