LXR alpha antibody [N1C2]
GTX113912
Overview
- SupplierGeneTex
- Product NameLXR alpha antibody [N1C2]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10062
- Target nameNR1H3
- Target descriptionnuclear receptor subfamily 1 group H member 3
- Target synonymsliver X nuclear receptor alpha variant 1; LXRA; LXR-a; oxysterols receptor LXR-alpha; RLD-1
- HostRabbit
- IsotypeIgG
- Protein IDQ13133
- Protein NameOxysterols receptor LXR-alpha
- Scientific DescriptionThe liver X receptors, LXRA and LXRB (NR1H2; MIM 600380), form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- A novel small molecule liver X receptor transcriptional regulator, nagilactone B, suppresses atherosclerosis in apoE-deficient mice. Gui Y et al., 2016 Oct, Cardiovasc ResRead more
- Betulin attenuates atherosclerosis in apoE-/- mice by up-regulating ABCA1 and ABCG1. Gui YZ et al., 2016 Sep, Acta Pharmacol SinRead more
Related products
Product group Antibodies
Nr1H3 Polyclonal AntibodyCAC07289
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
TargetNR1H3
- SizePrice
Product group Antibodies
LXR alpha Recombinant AntibodyBSM-54023R
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
TargetNR1H3
- SizePrice
Product group Antibodies
LXR alpha AntibodyABX430887
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
- SizePrice
Product group Antibodies
NR1H3 AntibodyCSB-PA004906
ApplicationsWestern Blot, ELISA
ReactivityHuman, Mouse, Rat
TargetNR1H3
- SizePrice
Product group Antibodies
NR1H3 / LXR Alpha AntibodyLS-C768622
ApplicationsImmunoHistoChemistry
TargetNR1H3
- SizePrice
Product group Antibodies
Anti-NR1H3 AntibodyHPA036443
ApplicationsWestern Blot, ImmunoHistoChemistry, Chip-exoSeq
TargetNR1H3
- SizePrice