WB analysis of various sample lysates using GTX54542 LXR alpha antibody. The signal was developed with ECL plus-Enhanced. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX54542 LXR alpha antibody. The signal was developed with ECL plus-Enhanced. Dilution : 1:1000 Loading : 25microg per lane
LXR alpha antibody
GTX54542
Overview
- SupplierGeneTex
- Product NameLXR alpha antibody
- Delivery Days Customer7
- Application Supplier NoteWB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10062
- Target nameNR1H3
- Target descriptionnuclear receptor subfamily 1 group H member 3
- Target synonymsliver X nuclear receptor alpha variant 1; LXRA; LXR-a; oxysterols receptor LXR-alpha; RLD-1
- HostRabbit
- IsotypeIgG
- Protein IDQ13133
- Protein NameOxysterols receptor LXR-alpha
- Scientific DescriptionThe protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- ReactivityMouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203