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WB analysis of various sample lysates using GTX54542 LXR alpha antibody. The signal was developed with ECL plus-Enhanced. Dilution : 1:1000 Loading : 25microg per lane

LXR alpha antibody

Name: LXR alpha antibody
SKU: GTX54542_G10
Availability: BackOrder

GTX54542

ApplicationsWestern Blot

DownloadDatasheet

Product group Antibodies

TargetNR1H3

Overview

Supplier
GeneTex
Product Name
LXR alpha antibody
Delivery Days Customer
7
Application Supplier Note
WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID10062
Target name
NR1H3
Target description
nuclear receptor subfamily 1 group H member 3
Target synonyms
liver X nuclear receptor alpha variant 1; LXRA; LXR-a; oxysterols receptor LXR-alpha; RLD-1
Host
Rabbit
Isotype
IgG
Protein IDQ13133
Protein Name
Oxysterols receptor LXR-alpha
Scientific Description
The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

LXR alpha antibody

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Overview

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