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ProductsBack/LXR beta antibody [N2C2], Internal

LXR beta antibody [N2C2], Internal

Research Use Only
GTX113571
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetNR1H2
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Overview

  • Supplier
    GeneTex
  • Product Name
    LXR beta antibody [N2C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID7376
  • Target name
    NR1H2
  • Target description
    nuclear receptor subfamily 1 group H member 2
  • Target synonyms
    liver X nuclear receptor beta; LX receptor beta; LXRB; LXR-b; NER; NER-I; nuclear orphan receptor LXR-beta; nuclear receptor NER; oxysterols receptor LXR-beta; RIP15; steroid hormone-nuclear receptor NER; ubiquitously-expressed nuclear receptor; UNR
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP55055
  • Protein Name
    Oxysterols receptor LXR-beta
  • Scientific Description
    The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995 [PubMed 7625741]).[supplied by OMIM]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Effect of TO901317 on GF to promote the differentiation of human bone marrow mesenchymal stem cells into dopamine neurons on Parkinsons disease. Li M et al., 2021, Ther Adv Chronic Dis
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  • Brain-derived neurotrophic factor modulates cholesterol homeostasis and Apolipoprotein E synthesis in human cell models of astrocytes and neurons. Spagnuolo MS et al., 2018 Sep, J Cell Physiol
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  • A novel small molecule liver X receptor transcriptional regulator, nagilactone B, suppresses atherosclerosis in apoE-deficient mice. Gui Y et al., 2016 Oct, Cardiovasc Res
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  • Betulin attenuates atherosclerosis in apoE-/- mice by up-regulating ABCA1 and ABCG1. Gui YZ et al., 2016 Sep, Acta Pharmacol Sin
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  • Inhibitory effect of Piper betel leaf extracts on copper-mediated LDL oxidation and oxLDL-induced lipid accumulation via inducing reverse cholesterol transport in macrophages. Ma GC et al., 2013 Dec 15, Food Chem
    Read more