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WB analysis of human bone marrow lysate using GTX89661 LXR beta antibody, N-term. Dilution : 1microg/ml Loading : 35microg protein in RIPA buffer
WB analysis of human bone marrow lysate using GTX89661 LXR beta antibody, N-term. Dilution : 1microg/ml Loading : 35microg protein in RIPA buffer
WB analysis of human bone marrow lysate using GTX89661 LXR beta antibody, N-term. Dilution : 1microg/ml Loading : 35microg protein in RIPA buffer

LXR beta antibody, N-term

GTX89661
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetNR1H2
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Overview

  • Supplier
    GeneTex
  • Product Name
    LXR beta antibody, N-term
  • Delivery Days Customer
    9
  • Antibody Specificity
    Based on the peptide used, this antibody is expected to be specific for LXR beta and not to cross-react with LXR alpha.
  • Application Supplier Note
    WB: 1-3microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.50 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7376
  • Target name
    NR1H2
  • Target description
    nuclear receptor subfamily 1 group H member 2
  • Target synonyms
    liver X nuclear receptor beta; LX receptor beta; LXRB; LXR-b; NER; NER-I; nuclear orphan receptor LXR-beta; nuclear receptor NER; oxysterols receptor LXR-beta; RIP15; steroid hormone-nuclear receptor NER; ubiquitously-expressed nuclear receptor; UNR
  • Host
    Goat
  • Isotype
    IgG
  • Protein IDP55055
  • Protein Name
    Oxysterols receptor LXR-beta
  • Scientific Description
    The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells. Candelaria NR et al., 2014, PLoS One
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  • Liver X receptor beta protects dopaminergic neurons in a mouse model of Parkinson disease. Dai YB et al., 2012 Aug 7, Proc Natl Acad Sci U S A
    Read more