
IHC-P analysis of human spleen using GTX89661 LXR beta antibody, N-term. Antigen retrieval : citrate buffer pH 6 Dilution : 3μg/ml
LXR beta antibody, N-term
GTX89661
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetNR1H2
Overview
- SupplierGeneTex
- Product NameLXR beta antibody, N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1-3microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID7376
- Target nameNR1H2
- Target descriptionnuclear receptor subfamily 1 group H member 2
- Target synonymsLXR-b, LXRB, NER, NER-I, RIP15, UNR, oxysterols receptor LXR-beta, LX receptor beta, liver X nuclear receptor beta, nuclear orphan receptor LXR-beta, nuclear receptor NER, steroid hormone-nuclear receptor NER, ubiquitously-expressed nuclear receptor
- HostGoat
- IsotypeIgG
- Protein IDP55055
- Protein NameOxysterols receptor LXR-beta
- Scientific DescriptionThe liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Candelaria NR, Addanki S, Zheng J, et al. Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells. PLoS One. 2014,9(9):e106289. doi: 10.1371/journal.pone.0106289Read this paper
- Dai YB, Tan XJ, Wu WF, et al. Liver X receptor β protects dopaminergic neurons in a mouse model of Parkinson disease. Proc Natl Acad Sci U S A. 2012,109(32):13112-7. doi: 10.1073/pnas.1210833109Read this paper








