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LXRA antibody

Research Use Only
ORB67061
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetNR1H3
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Overview

  • Supplier
    Biorbyt
  • Product Name
    LXRA antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID10062
  • Target name
    NR1H3
  • Target description
    nuclear receptor subfamily 1 group H member 3
  • Target synonyms
    liver X nuclear receptor alpha variant 1; LXRA; LXR-a; oxysterols receptor LXR-alpha; RLD-1
  • Host
    Rabbit
  • Protein IDQ13133
  • Protein Name
    Oxysterols receptor LXR-alpha
  • Scientific Description
    Rabbit polyclonal to LXRA.Liver X receptor alpha (LXRA) belongs to the nuclear hormone receptor family, NR1 subfamily. LXRAis an orphan receptor. LXRA can form a heterodimer with RXR, which shifts RXR from a silent DNAbindingpartner to an active ligand-binding subunit in mediating retinoid responses through targetgenes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats oftwo similar hexanuclotide half-sites spaced by four nucleotides. LXRA plays an important role in theregulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependentubiquitination of LDLR, VLDLR and LRP8.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203