MAdCAM-1 antibody [17F5]

GeneTex

MAdCAM-1 antibody [17F5]

9

This antibody recognizes the mucin domain of MAdCAM-1. This antibody does not block the function of MAdCAM-1.

IHC-P: 1/50-1/100. FACS: 1/10-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

17F5

1 mg/ml

Unconjugated

MADCAM1

mucosal vascular addressin cell adhesion molecule 1

hMAdCAM-1; MACAM1; MAdCAM-1; mucosal addressin cell adhesion molecule 1

Mouse

IgG1

Mucosal addressin cell adhesion molecule 1

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

Camel, Human

-20°C or -80°C,2°C to 8°C

12352203