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Western Blot analysis of Jurkat and PC3 cell using MCTS1 Polyclonal Antibody at dilution of 1:200
Western Blot analysis of Jurkat and PC3 cell using MCTS1 Polyclonal Antibody at dilution of 1:200
Western Blot analysis of Jurkat and PC3 cell using MCTS1 Polyclonal Antibody at dilution of 1:200

MCTS1 Polyclonal Antibody

Research Use Only
E-AB-15193
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    MCTS1 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA WB IHC
  • Certification
    Research Use Only
  • Concentration
    0.2mg/ml
  • Scientific Description
    MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.
  • UNSPSC
    12352203