
IHC-P analysis of human hepatocarcinoma using GTX81955 MDH1 antibody, C-term.
MDH1 antibody, C-term
GTX81955
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMDH1
Overview
- SupplierGeneTex
- Product NameMDH1 antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. IHC-P: 1:10-1:50. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4190
- Target nameMDH1
- Target descriptionmalate dehydrogenase 1
- Target synonymscytosolic malate dehydrogenase; DEE88; diiodophenylpyruvate reductase; EIEE88; epididymis secretory protein Li 32; HEL-S-32; KAR; malate dehydrogenase 1, NAD (soluble); malate dehydrogenase, cytoplasmic; malate dehydrogenase, peroxisomal; MDHA; MDH-s; MGC:1375; MOR2; soluble malate dehydrogenase
- HostRabbit
- IsotypeIgG
- Protein IDP40925
- Protein NameMalate dehydrogenase, cytoplasmic
- Scientific DescriptionThis gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6. [provided by RefSeq, Feb 2016]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Quantitative proteomic analysis of human lung tumor xenografts treated with the ectopic ATP synthase inhibitor citreoviridin. Wu YH et al., 2013, PLoS OneRead more