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IHC-P analysis of human hepatocarcinoma using GTX81955 MDH1 antibody, C-term.
IHC-P analysis of human hepatocarcinoma using GTX81955 MDH1 antibody, C-term.
IHC-P analysis of human hepatocarcinoma using GTX81955 MDH1 antibody, C-term.

MDH1 antibody, C-term

GTX81955
GeneTex
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMDH1
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Overview

  • Supplier
    GeneTex
  • Product Name
    MDH1 antibody, C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. IHC-P: 1:10-1:50. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID4190
  • Target name
    MDH1
  • Target description
    malate dehydrogenase 1
  • Target synonyms
    DEE88, EIEE88, HEL-S-32, KAR, MDH-s, MDHA, MGC:1375, MOR2, malate dehydrogenase, cytoplasmic, malate dehydrogenase, peroxisomal, aromatic alpha-keto acid reductase, cytosolic malate dehydrogenase, diiodophenylpyruvate reductase, epididymis secretory protein Li 32, malate dehydrogenase 1, NAD (soluble), soluble malate dehydrogenase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP40925
  • Protein Name
    Malate dehydrogenase, cytoplasmic
  • Scientific Description
    This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6. [provided by RefSeq, Feb 2016]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Quantitative proteomic analysis of human lung tumor xenografts treated with the ectopic ATP synthase inhibitor citreoviridin. Wu YH et al., 2013, PLoS One
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