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mGluR3 antibody - Overexpression Validated

Research Use Only
GTX70719
GeneTex
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rat
TargetGRM3

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Overview

  • Supplier
    GeneTex
  • Product Name
    mGluR3 antibody - Overexpression Validated
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2913
  • Target name
    GRM3
  • Target description
    glutamate metabotropic receptor 3
  • Target synonyms
    GLUR3; glutamate receptor, metabotropic 3; GPRC1C; metabotropic glutamate receptor 3; mGlu3; MGLUR3
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Jul 2008]
  • Reactivity
    Bovine, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rat
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203