mGluR3 antibody - Overexpression Validated
GTX70719
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rat
TargetGRM3
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Overview
- SupplierGeneTex
- Product NamemGluR3 antibody - Overexpression Validated
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2913
- Target nameGRM3
- Target descriptionglutamate metabotropic receptor 3
- Target synonymsGLUR3; glutamate receptor, metabotropic 3; GPRC1C; metabotropic glutamate receptor 3; mGlu3; MGLUR3
- HostRabbit
- IsotypeIgG
- Scientific DescriptionL-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Jul 2008]
- ReactivityBovine, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203