![IHC-P analysis of human glioblastoma (GBM) tissue using GTX641400 mGluR5 antibody [H339] HistoMAX?. Glioblastoma with moderate to strong mGluR5 staining of most tumor cells. IHC-P analysis of human glioblastoma (GBM) tissue using GTX641400 mGluR5 antibody [H339] HistoMAX?. Glioblastoma with moderate to strong mGluR5 staining of most tumor cells.](https://www.genetex.com/upload/website/prouct_img/normal/GTX641400/GTX641400_20250117_IHC-P_1_25012200_610.webp)
IHC-P analysis of human glioblastoma (GBM) tissue using GTX641400 mGluR5 antibody [H339] HistoMAX?. Glioblastoma with moderate to strong mGluR5 staining of most tumor cells.
mGluR5 antibody [H339] HistoMAX(tm)
GTX641400
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetGRM5
Overview
- SupplierGeneTex
- Product NamemGluR5 antibody [H339] HistoMAX(tm)
- Delivery Days Customer7
- Application Supplier NoteIHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDH339
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2915
- Target nameGRM5
- Target descriptionglutamate metabotropic receptor 5
- Target synonymsGPRC1E, MGLUR5, PPP1R86, mGlu5, metabotropic glutamate receptor 5, glutamate receptor, metabotropic 5, protein phosphatase 1, regulatory subunit 86
- HostRabbit
- IsotypeIgG
- Protein IDP41594
- Protein NameMetabotropic glutamate receptor 5
- Scientific DescriptionThis gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
![IHC-P analysis of human normal tissues using GTX641400 mGluR5 antibody [H339] HistoMAX?. A strong mGluR5 immunostaining in the hippocampus. IHC-P analysis of human normal tissues using GTX641400 mGluR5 antibody [H339] HistoMAX?. A strong mGluR5 immunostaining in the hippocampus.](https://www.genetex.com/upload/website/prouct_img/normal/GTX641400/GTX641400_20250117_IHC-P_Array_25012200_328.webp)
![IHC-P analysis of human hippocampus tissue using GTX641400 mGluR5 antibody [H339] HistoMAX?. mGluR5 is strongly expressed in the hippocampus. IHC-P analysis of human hippocampus tissue using GTX641400 mGluR5 antibody [H339] HistoMAX?. mGluR5 is strongly expressed in the hippocampus.](https://www.genetex.com/upload/website/prouct_img/normal/GTX641400/GTX641400_20250117_IHC-P_2_25012200_707.webp)
![IHC-P analysis of human muscular wall from appendix tissue using GTX641400 mGluR5 antibody [H339] HistoMAX?. Weak to moderate mGluR5 staining of nerve fibers. IHC-P analysis of human muscular wall from appendix tissue using GTX641400 mGluR5 antibody [H339] HistoMAX?. Weak to moderate mGluR5 staining of nerve fibers.](https://www.genetex.com/upload/website/prouct_img/normal/GTX641400/GTX641400_20250117_IHC-P_3_25012200_644.webp)





![Boiled and unboiled various tissue extracts (50 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with mGluR5 antibody [HL2543] (GTX638912) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.](https://www.genetex.com/upload/website/prouct_img/normal/GTX638912/GTX638912_T-45124_20230818_WB_M_R_23082201_444.webp)