mGluR7 antibody
GTX71713
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Equine, Human, Monkey, Mouse, Rat
TargetGRM7
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Overview
- SupplierGeneTex
- Product NamemGluR7 antibody
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2917
- Target nameGRM7
- Target descriptionglutamate metabotropic receptor 7
- Target synonymsGLUR7; glutamate receptor, metabotropic 7; GPRC1G; metabotropic glutamate receptor 7; MGLU7; MGLUR7; NEDSHBA; PPP1R87; protein phosphatase 1, regulatory subunit 87
- HostRabbit
- IsotypeIgG
- Scientific DescriptionL-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
- ReactivityBovine, Canine, Equine, Human, Monkey, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203