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WB analysis of various cell lines using GTX84507 Mig-2 antibody [9E4]. Loading : 35 ug per lane
WB analysis of various cell lines using GTX84507 Mig-2 antibody [9E4]. Loading : 35 ug per lane
WB analysis of various cell lines using GTX84507 Mig-2 antibody [9E4]. Loading : 35 ug per lane

Mig-2 antibody [9E4]

GTX84507
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Human, Monkey, Rat
TargetFERMT2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Mig-2 antibody [9E4]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:2000. ICC/IF: 1:50. IHC-P: 1:150. IP: 2ug/500ul. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10979
  • Target name
    FERMT2
  • Target description
    FERM domain containing kindlin 2
  • Target synonyms
    KIND2, MIG2, PLEKHC1, UNC112, UNC112B, mig-2, fermitin family homolog 2, PH domain-containing family C member 1, fermitin family member 2, kindlin 2, mitogen inducible gene 2 protein, mitogen inducible gene-2, pleckstrin homology domain containing, family C (with FERM domain) member 1, pleckstrin homology domain containing, family C member 1
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDQ96AC1
  • Protein Name
    Fermitin family homolog 2
  • Scientific Description
    Participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites.
  • Reactivity
    Canine, Human, Monkey, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    41116161

References

  • Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Abeta and TAU proteostasis. Sullivan SE et al., 2019 Mar 1, Hum Mol Genet
    Read this paper
  • Genome-wide, high-content siRNA screening identifies the Alzheimers genetic risk factor FERMT2 as a major modulator of APP metabolism. Chapuis J et al., 2017 Jun, Acta Neuropathol
    Read this paper

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