ICC/IF analysis of HepG2 cells using GTX84507 Mig-2 antibody [9E4].
![IHC-P analysis of human breast adenocarcinoma tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84507/GTX84507_2799_IHC-P_w_23061420_796.webp "IHC-P analysis of human breast adenocarcinoma tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human ovary adenocarcinoma tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84507/GTX84507_2800_IHC-P_w_23061420_769.webp "IHC-P analysis of human ovary adenocarcinoma tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human kidney carcinoma tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84507/GTX84507_2801_IHC-P_w_23061420_943.webp "IHC-P analysis of human kidney carcinoma tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human lung carcinoma tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84507/GTX84507_2802_IHC-P_w_23061420_438.webp "IHC-P analysis of human lung carcinoma tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human colon tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84507/GTX84507_2803_IHC-P_w_23061420_503.webp "IHC-P analysis of human colon tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human endometrium tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84507/GTX84507_2804_IHC-P_w_23061420_168.webp "IHC-P analysis of human endometrium tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human ovary tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84507/GTX84507_2805_IHC-P_w_23061420_433.webp "IHC-P analysis of human ovary tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human pancreas tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84507/GTX84507_2806_IHC-P_w_23061420_494.webp "IHC-P analysis of human pancreas tissue using GTX84507 Mig-2 antibody [9E4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IP analysis of DDDDK tagged Mig-2 overexpressed HEK293T lysate using GTX84507 Mig-2 antibody [9E4].After extensive wash to remove any non-specific binding, the immuno-precipitated products were analyzed with rabbit anti-DDDDK polyclonal antibody. IP reaction : 2microg antibody / 500microl cell lysate](https://www.genetex.com/upload/website/prouct_img/normal/GTX84507/GTX84507_3371_IP_w_23061420_129.webp "IP analysis of DDDDK tagged Mig-2 overexpressed HEK293T lysate using GTX84507 Mig-2 antibody [9E4].After extensive wash to remove any non-specific binding, the immuno-precipitated products were analyzed with rabbit anti-DDDDK polyclonal antibody. IP reaction : 2microg antibody / 500microl cell lysate")
ICC/IF analysis of HepG2 cells using GTX84507 Mig-2 antibody [9E4].
Mig-2 antibody [9E4]
GTX84507
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Human, Monkey, Rat
TargetFERMT2
Overview
- SupplierGeneTex
- Product NameMig-2 antibody [9E4] - KO/KD, Overexpression Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:2000. ICC/IF: 1:50. IHC-P: 1:150. IP: 2ug/500ul. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10979
- Target nameFERMT2
- Target descriptionFERM domain containing kindlin 2
- Target synonymsfermitin family homolog 2; fermitin family member 2; KIND2; kindlin 2; MIG2; mig-2; mitogen inducible gene 2 protein; mitogen inducible gene-2; PH domain-containing family C member 1; pleckstrin homology domain containing, family C (with FERM domain) member 1; pleckstrin homology domain containing, family C member 1; PLEKHC1; UNC112; UNC112B
- HostMouse
- IsotypeIgG2a
- Protein IDQ96AC1
- Protein NameFermitin family homolog 2
- Scientific DescriptionParticipates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites.
- ReactivityCanine, Human, Monkey, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Abeta and TAU proteostasis. Sullivan SE et al., 2019 Mar 1, Hum Mol GenetRead more
- Genome-wide, high-content siRNA screening identifies the Alzheimers genetic risk factor FERMT2 as a major modulator of APP metabolism. Chapuis J et al., 2017 Jun, Acta NeuropatholRead more