Western Blot analysis of various samples using Mineralocorticoid receptor Polyclonal Antibody at dilution of 1:600.
Western Blot analysis of various samples using Mineralocorticoid receptor Polyclonal Antibody at dilution of 1:600.
Mineralocorticoid receptor Polyclonal Antibody
E-AB-70260
Product group Antibodies
Overview
- SupplierElabscience
- Product NameMineralocorticoid receptor Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
- UNSPSC12352203