Mineralocorticoid receptor Polyclonal Antibody
RD70461A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetNR3C2
Overview
- SupplierReddot Biotech
- Product NameMineralocorticoid receptor Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.3 mg/ml
- ConjugateUnconjugated
- Gene ID4306
- Target nameNR3C2
- Target descriptionnuclear receptor subfamily 3 group C member 2
- Target synonymsaldosterone receptor; MCR; mineralocorticoid receptor; mineralocorticoid receptor 1; mineralocorticoid receptor 2; mineralocorticoid receptor delta; MLR; MR; NR3C2VIT; nuclear receptor subfamily 3, group C, member 2 variant 3
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203