Bio-Connect

Mineralocorticoid receptor Polyclonal Antibody

RD70461A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetNR3C2
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    Mineralocorticoid receptor Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.3 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4306
  • Target name
    NR3C2
  • Target description
    nuclear receptor subfamily 3 group C member 2
  • Target synonyms
    aldosterone receptor; MCR; mineralocorticoid receptor; mineralocorticoid receptor 1; mineralocorticoid receptor 2; mineralocorticoid receptor delta; MLR; MR; NR3C2VIT; nuclear receptor subfamily 3, group C, member 2 variant 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203