
WB analysis of extracts from mouse brain tissue using GTX55417 MITF (phospho Ser180/73) antibody. Left : Primary antibody Right : Primary antibody pre-incubated with the antigen specific peptide
MITF (phospho Ser180/73) antibody
GTX55417
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetMITF
Overview
- SupplierGeneTex
- Product NameMITF (phospho Ser180/73) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4286
- Target nameMITF
- Target descriptionmelanocyte inducing transcription factor
- Target synonymsCMM8, COMMAD, MI, MITF-A, WS2, WS2A, bHLHe32, microphthalmia-associated transcription factor, class E basic helix-loop-helix protein 32, melanogenesis associated transcription factor, microphtalmia-associated transcription factor
- HostRabbit
- IsotypeIgG
- Protein IDO75030
- Protein NameMicrophthalmia-associated transcription factor
- Scientific DescriptionThe protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Hseu YC, Vudhya Gowrisankar Y, Wang LW, et al. The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated α-MSH in keratinocytes via Nrf2-mediated antioxidant pathways. Redox Biol. 2021,44:102007. doi: 10.1016/j.redox.2021.102007Read this paper

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