IHC-P analysis of human esophagus tissue using GTX57187 MLH1 antibody [IHC409]
IHC-P analysis of human esophagus tissue using GTX57187 MLH1 antibody [IHC409]
MLH1 antibody [IHC409]
GTX57187
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMLH1
Overview
- SupplierGeneTex
- Product NameMLH1 antibody [IHC409]
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDIHC409
- ConjugateUnconjugated
- Gene ID4292
- Target nameMLH1
- Target descriptionmutL homolog 1
- Target synonymsCOCA2; DNA mismatch repair protein Mlh1; FCC2; hMLH1; HNPCC; HNPCC2; MMRCS1; mutL homolog 1, colon cancer, nonpolyposis type 2
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionThis gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203