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Mouse anti Human ATIC

Research Use Only
X2062M
Nordic-MUbio
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityAmphibian, Drosophila, Human, Mouse, Rat
TargetATIC
Price on request
200 ug
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Overview

  • Supplier
    Nordic-MUbio
  • Product Name
    Mouse anti Human ATIC
  • Delivery Days Customer
    7
  • Application Supplier Note
    Antibody can be used for Western blotting (1-2 microg/ml) and immunohistochemistry on formalin-fixed, paraffin-embedded tissues (1-5 microg/ml). Optimal concentration should be evaluated by serial dilutions.
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Applications Supplier
    Western Blotting;Western Blotting;Immunohistochemistry
  • Category Supplier
    Primary antibodies
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    F38 P7 H9
  • Conjugate
    Unconjugated
  • Gene ID471
  • Target name
    ATIC
  • Target description
    5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  • Target synonyms
    5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase; AICAR; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICAR transformylase/inosine monophosphate cyclohydrolase; AICARFT; AICARFT/IMPCHASE; bifunctional purine biosynthesis protein ATIC; bifunctional purine biosynthesis protein PURH; epididymis secretory sperm binding protein Li 70p; HEL-S-70p; IMPCHASE; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PURH
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP31939
  • Protein Name
    Bifunctional purine biosynthesis protein PURH
  • Scientific Description
    AICAR; AICARFT; AICARFT/IMPCHASE; PURH; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  • Shelf life instruction
    See expiration date on vial
  • Reactivity
    Amphibian, Drosophila, Human, Mouse, Rat
  • Reactivity Supplier
    Human;Frog;Fruit Fly;Rat;Mouse
  • Reactivity Supplier Note
    Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the human ATIC protein and mouse myeloma Ag8563 cells. Sequence common in frog, fruit fly, rat and mouse.
  • UNSPSC
    12352203

References

  • 1. Bulock, K.G., et al. (2002). The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate channeling. J. Biol. Chem. 277(25):22168-22174. 2. Marie, S., et al. (2004). AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC. Am. J. Hum. Genet. 74(6):1276-1281.