MVP/LRP antibody
GTX113601
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMVP
Overview
- SupplierGeneTex
- Product NameMVP/LRP antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9961
- Target nameMVP
- Target descriptionmajor vault protein
- Target synonymsLRP; lung resistance-related protein; major vault protein; testicular secretory protein Li 30; VAULT1
- HostRabbit
- IsotypeIgG
- Protein IDQ14764
- Protein NameMajor vault protein
- Scientific DescriptionThis gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Immunoediting role for major vault protein in apoptotic signaling induced by bacterial N-acyl homoserine lactones. Rayo J et al., 2021 Mar 23, Proc Natl Acad Sci U S ARead more