Myeloperoxidase antibody [2C7]
GTX75318
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMPO
Overview
- SupplierGeneTex
- Product NameMyeloperoxidase antibody [2C7]
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1/500-1/1,000. IHC-Fr: 1/1,000-1/5,000. FACS: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2C7
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4353
- Target nameMPO
- Target descriptionmyeloperoxidase
- Target synonymsmyeloperoxidase
- HostMouse
- IsotypeIgG1
- Protein IDP05164
- Protein NameMyeloperoxidase
- Scientific DescriptionMyeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Gasdermin D-dependent platelet pyroptosis exacerbates NET formation and inflammation in severe sepsis.Read more
- Decreased Tissue Omega-6/Omega-3 Fatty Acid Ratio Prevents Chemotherapy-Induced Gastrointestinal Toxicity Associated with Alterations of Gut Microbiome. Kaliannan K et al., 2022 May 10, Int J Mol SciRead more
- An Autopsy Case of Myeloperoxidase-anti-neutrophil Cytoplasmic Antibody (MPO-ANCA)-associated Vasculitis Accompanied by Cryoglobulinemic Vasculitis Affecting the Kidneys, Skin, and Gastrointestinal Tract. Hasegawa J et al., 2018 Sep 15, Intern MedRead more
- Vanishing Immunoglobulins: The Formation of Pauci-Immune Lesions in Myeloperoxidase-Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Futamata E et al., 2018, NephronRead more
- Capsular polysaccharides from Cryptococcus neoformans modulate production of neutrophil extracellular traps (NETs) by human neutrophils. Rocha JD et al., 2015 Jan 26, Sci RepRead more
- LRRK2 is involved in the IFN-gamma response and host response to pathogens. Gardet A et al., 2010 Nov 1, J ImmunolRead more
- Signalling mechanisms for Toll-like receptor-activated neutrophil exocytosis: key roles for interleukin-1-receptor-associated kinase-4 and phosphatidylinositol 3-kinase but not Toll/IL-1 receptor (TIR) domain-containing adaptor inducing IFN-beta (TRIF). Brzezinska AA et al., 2009 Jul, ImmunologyRead more
Datasheet
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