![FACS analysis of PC-2 cells using GTX82992 N-Cadherin antibody [5D5]. Green : N-Cadherin Purple : negative control FACS analysis of PC-2 cells using GTX82992 N-Cadherin antibody [5D5]. Green : N-Cadherin Purple : negative control](https://www.genetex.com/upload/website/prouct_img/normal/GTX82992/GTX82992_20170912_FACS_w_23061322_686.webp)
FACS analysis of PC-2 cells using GTX82992 N-Cadherin antibody [5D5]. Green : N-Cadherin Purple : negative control
N-Cadherin antibody [5D5]
GTX82992
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCDH2
Overview
- SupplierGeneTex
- Product NameN-Cadherin antibody [5D5]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. FACS: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5D5
- ConjugateUnconjugated
- Gene ID1000
- Target nameCDH2
- Target descriptioncadherin 2
- Target synonymsACOGS, ADHD8, ARVD14, CD325, CDHN, CDw325, NCAD, cadherin-2, N-cadherin 1, cadherin 2, type 1, N-cadherin (neuronal), calcium-dependent adhesion protein, neuronal, neural cadherin
- HostMouse
- IsotypeIgG1
- Protein IDP19022
- Protein NameCadherin-2
- Scientific DescriptionThis gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Zeng B, Li Y, Jiang F, et al. LncRNA GAS5 suppresses proliferation, migration, invasion, and epithelial-mesenchymal transition in oral squamous cell carcinoma by regulating the miR-21/PTEN axis. Exp Cell Res. 2019,374(2):365-373. doi: 10.1016/j.yexcr.2018.12.014Read this paper
- Saydaminova K, Strauss R, Xie M, et al. Sensitizing ovarian cancer cells to chemotherapy by interfering with pathways that are involved in the formation of cancer stem cells. Cancer Biol Ther. 2016,17(10):1079-1088.Read this paper
![ICC/IF analysis of A431 cells using GTX82992 N-Cadherin antibody [5D5]. Green : N-Cadherin Blue: DRAQ5 fluorescent DNA dye ICC/IF analysis of A431 cells using GTX82992 N-Cadherin antibody [5D5]. Green : N-Cadherin Blue: DRAQ5 fluorescent DNA dye](https://www.genetex.com/upload/website/prouct_img/normal/GTX82992/GTX82992_20170912_ICCIF_w_23061322_890.webp)
![IHC-P analysis of human Placenta tissue using GTX82992 N-Cadherin antibody [5D5]. IHC-P analysis of human Placenta tissue using GTX82992 N-Cadherin antibody [5D5].](https://www.genetex.com/upload/website/prouct_img/normal/GTX82992/GTX82992_20170912_IHC-P_1_w_23061322_547.webp)
![IHC-P analysis of human lung cancer (A), colon cancer (B), ovarian cancer (C) and mammary cancer(D) using GTX82992 N-Cadherin antibody [5D5]. IHC-P analysis of human lung cancer (A), colon cancer (B), ovarian cancer (C) and mammary cancer(D) using GTX82992 N-Cadherin antibody [5D5].](https://www.genetex.com/upload/website/prouct_img/normal/GTX82992/GTX82992_20170912_IHC-P_w_23061322_220.webp)
![WB analysis of A431 (1), NIH3T3 (2), HeLa (3), C6 (4) and LNCap (5) cell lysate using GTX82992 N-Cadherin antibody [5D5]. WB analysis of A431 (1), NIH3T3 (2), HeLa (3), C6 (4) and LNCap (5) cell lysate using GTX82992 N-Cadherin antibody [5D5].](https://www.genetex.com/upload/website/prouct_img/normal/GTX82992/GTX82992_20170912_WB_w_23061322_960.webp)





![IHC-P analysis of human breast tissue using GTX19348 N-Cadherin antibody [8C11]. A : isotype control B : Primary antibody C : Primary antibody with magnified section Antigen retrieval : HEIR with a buffer (pH 6.2) Dilution : 2 microg/ml](https://www.genetex.com/upload/website/prouct_img/normal/GTX19348/GTX19348_1068_IHC-P_w_23060620_515.webp)