Bio-Connect

N-Cadherin antibody [N1N3]

GTX112734
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCDH2
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    N-Cadherin antibody [N1N3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.19 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1000
  • Target name
    CDH2
  • Target description
    cadherin 2
  • Target synonyms
    ACOGS; ARVD14; cadherin 2, type 1, N-cadherin (neuronal); cadherin-2; calcium-dependent adhesion protein, neuronal; CD325; CDHN; CDw325; NCAD; N-cadherin 1; neural cadherin
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP19022
  • Protein Name
    Cadherin-2
  • Scientific Description
    This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Cleavage stimulation factor 2 promotes malignant progression of liver hepatocellular carcinoma by activating phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin pathway. Zhang MH et al., 2022 Apr, Bioengineered
    Read more
  • Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3beta-beta-Catenin and XIAP-Survivin Pathways. Chang YX et al., 2020 Dec 21, Cancers (Basel)
    Read more
  • miR-140 targeting CTSB signaling suppresses the mesenchymal transition and enhances temozolomide cytotoxicity in glioblastoma multiforme. Ho KH et al., 2019 Sep, Pharmacol Res
    Read more
  • Elevation of YAP promotes the epithelial-mesenchymal transition and tumor aggressiveness in colorectal cancer. Ling HH et al., 2017 Jan 1, Exp Cell Res
    Read more
  • Overexpression of lipocalin 2 in human cervical cancer enhances tumor invasion. Chung IH et al., 2016 Mar 8, Oncotarget
    Read more
  • N-cadherin coordinates AMP kinase-mediated lung vascular repair. Jian MY et al., 2016 Jan 1, Am J Physiol Lung Cell Mol Physiol
    Read more
  • Involvement of RARRES3 in the regulation of Wnt proteins acylation and signaling activities in human breast cancer cells. Hsu TH et al., 2015 May, Cell Death Differ
    Read more
  • CD63 tetraspanin is a negative driver of epithelial-to-mesenchymal transition in human melanoma cells. Lupia A et al., 2014 Dec, J Invest Dermatol
    Read more