Bio-Connect

N-Cadherin antibody [N1N3]

GTX112734
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCDH2
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Overview

  • Supplier
    GeneTex
  • Product Name
    N-Cadherin antibody [N1N3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.19 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1000
  • Target name
    CDH2
  • Target description
    cadherin 2
  • Target synonyms
    ACOGS, ADHD8, ARVD14, CD325, CDHN, CDw325, NCAD, cadherin-2, N-cadherin 1, cadherin 2, type 1, N-cadherin (neuronal), calcium-dependent adhesion protein, neuronal, neural cadherin
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP19022
  • Protein Name
    Cadherin-2
  • Scientific Description
    This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Cleavage stimulation factor 2 promotes malignant progression of liver hepatocellular carcinoma by activating phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin pathway. Zhang MH et al., 2022 Apr, Bioengineered
    Read more
  • Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3beta-beta-Catenin and XIAP-Survivin Pathways. Chang YX et al., 2020 Dec 21, Cancers (Basel)
    Read more
  • miR-140 targeting CTSB signaling suppresses the mesenchymal transition and enhances temozolomide cytotoxicity in glioblastoma multiforme. Ho KH et al., 2019 Sep, Pharmacol Res
    Read more
  • Elevation of YAP promotes the epithelial-mesenchymal transition and tumor aggressiveness in colorectal cancer. Ling HH et al., 2017 Jan 1, Exp Cell Res
    Read more
  • Overexpression of lipocalin 2 in human cervical cancer enhances tumor invasion. Chung IH et al., 2016 Mar 8, Oncotarget
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  • N-cadherin coordinates AMP kinase-mediated lung vascular repair. Jian MY et al., 2016 Jan 1, Am J Physiol Lung Cell Mol Physiol
    Read more
  • Involvement of RARRES3 in the regulation of Wnt proteins acylation and signaling activities in human breast cancer cells. Hsu TH et al., 2015 May, Cell Death Differ
    Read more
  • CD63 tetraspanin is a negative driver of epithelial-to-mesenchymal transition in human melanoma cells. Lupia A et al., 2014 Dec, J Invest Dermatol
    Read more