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Chemical Structure
Chemical Structure
Chemical Structure

NAI-112 [1498289-64-7]

Research Use Only
AG-CN2-0309
AdipoGen Life Sciences
CAS Number1498289-64-7
Product group Chemicals
Estimated Purity>80% (HPLC)
Molecular Weight2367.6
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    NAI-112 [1498289-64-7]
  • Delivery Days Customer
    10
  • CAS Number
    1498289-64-7
  • Certification
    Research Use Only
  • Estimated Purity
    >80% (HPLC)
  • Hazard Information
    Non-hazardous
  • Molecular Formula
    C109H147N25O31S2
  • Molecular Weight
    2367.6
  • Scientific Description
    Chemical. CAS: 1498289-64-7. Formula: C109H147N25O31S2. MW: 2367.6. Isolated from Actinoplanes sp. Labionin-containing class III lanthipeptide. Antinociceptive agent. Effective in animal models of nociceptic and inflammatory pain. Does not act through opioid, cannabinoid or descending adrenergic mechanisms. Most likely acts through the vanilloid-sensitive pathway by a novel target. It can be developed for the treatment of neuropathic pain. Weak antibacterial compound. - Labionin-containing class III lanthipeptide. Antinociceptive agent. Effective in animal models of nociceptic and inflammatory pain. Does not act through opioid, cannabinoid or descending adrenergic mechanisms. Most likely acts through the vanilloid-sensitive pathway by a novel target. It can be developed for the treatment of neuropathic pain. Weak antibacterial compound.
  • SMILES
    O=C(NC(CC1(C(NC(CC2=CNC3=C2C=CC=C3)C(NC(CO)C(NC(CC(N)=O)C(NC(C(O)=O)CSC1C)=O)=O)=O)=O)NC4=O)C(NC(CO)C(NC4CC5=CC=CC=C5)=O)=O)C6CCCN6C(C(CC7=CN(C8OC(C)C(O)C(O)C8O)C9=C7C=CC=C9)NC(CNC(C%10N(C(C(CSC%11)NC(C%12N(CCC%12)C(C(CO)NC(C(CO)NC(C(C(C)C)NC(C%11%13NC(C(CC(C)C)NC(/C(NC(C(C%13)NC(C(C(C)C)N)=O)=O)=C/C)=O)=O)=O)=O)=O)=O)=O)=O)CCC%10)=O)=O)=O
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity: M. Iorio, et al.; ACS Chem. Biol. 9, 398 (2014)
  • Discovering new bioactive molecules from microbial sources: P. Monciardini, et al.; Microb. Biotechnol. 7, 209 (2014) (Review)