Chemical Structure
NAI-112 [1498289-64-7]
AG-CN2-0309
Overview
- SupplierAdipoGen Life Sciences
- Product NameNAI-112
- Delivery Days Customer10
- CAS Number1498289-64-7
- CertificationResearch Use Only
- Estimated Purity>80%
- Molecular FormulaC109H147N25O31S2
- Molecular Weight2367.6
- Scientific DescriptionChemical. CAS: 1498289-64-7. Formula: C109H147N25O31S2. MW: 2367.6. Isolated from Actinoplanes sp. Labionin-containing class III lanthipeptide. Antinociceptive agent. Effective in animal models of nociceptic and inflammatory pain. Does not act through opioid, cannabinoid or descending adrenergic mechanisms. Most likely acts through the vanilloid-sensitive pathway by a novel target. It can be developed for the treatment of neuropathic pain. Weak antibacterial compound. - Labionin-containing class III lanthipeptide. Antinociceptive agent. Effective in animal models of nociceptic and inflammatory pain. Does not act through opioid, cannabinoid or descending adrenergic mechanisms. Most likely acts through the vanilloid-sensitive pathway by a novel target. It can be developed for the treatment of neuropathic pain. Weak antibacterial compound.
- SMILESO=C(NC(CC1(C(NC(CC2=CNC3=C2C=CC=C3)C(NC(CO)C(NC(CC(N)=O)C(NC(C(O)=O)CSC1C)=O)=O)=O)=O)NC4=O)C(NC(CO)C(NC4CC5=CC=CC=C5)=O)=O)C6CCCN6C(C(CC7=CN(C8OC(C)C(O)C(O)C8O)C9=C7C=CC=C9)NC(CNC(C%10N(C(C(CSC%11)NC(C%12N(CCC%12)C(C(CO)NC(C(CO)NC(C(C(C)C)NC(C%11%13NC(C(CC(C)C)NC(/C(NC(C(C%13)NC(C(C(C)C)N)=O)=O)=C/C)=O)=O)=O)=O)=O)=O)=O)=O)CCC%10)=O)=O)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
References
- A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity: M. Iorio, et al.; ACS Chem. Biol. 9, 398 (2014)
- Discovering new bioactive molecules from microbial sources: P. Monciardini, et al.; Microb. Biotechnol. 7, 209 (2014) (Review)