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ProductsBack/NAMPT Polyclonal Antibody

NAMPT Polyclonal Antibody

RD240013A

ApplicationsWestern Blot, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman, Rat

TargetNAMPT

Overview

Supplier
Reddot Biotech
Product Name
NAMPT Polyclonal Antibody
Delivery Days Customer
5
Applications
Western Blot, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Concentration
2 mg/ml
Conjugate
Unconjugated
Gene ID10135
Target name
NAMPT
Target description
nicotinamide phosphoribosyltransferase
Target synonyms
1110035O14Rik, PBEF, PBEF1, VF, VISFATIN, nicotinamide phosphoribosyltransferase, NAmPRTase, pre-B cell-enhancing factor, pre-B-cell colony-enhancing factor 1
Host
Rabbit
Isotype
IgG
Scientific Description
Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus (T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.
Reactivity
Human, Rat
Storage Instruction
-20°C
UNSPSC
12352203

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