NBS1 antibody [1C3]

GeneTex

NBS1 antibody [1C3] - KO/KD Validated

9

WB: 1:500-1:3000. ICC/IF: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

1C3

1 mg/ml

Unconjugated

NBN

nibrin

AT-V1, AT-V2, ATV, NBS, NBS1, P95, hNbs1, nibrin, Nijmegen breakage syndrome 1 (nibrin), cell cycle regulatory protein p95, p95 protein of the MRE11/RAD50 complex

Mouse

IgG1

Nibrin

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203