WB analysis of extracts from HeLa cells untreated or treated with Hydroxyurea using GTX50131 NBS1 (phospho Ser343) antibody.
WB analysis of extracts from HeLa cells untreated or treated with Hydroxyurea using GTX50131 NBS1 (phospho Ser343) antibody.
NBS1 (phospho Ser343) antibody
GTX50131
Overview
- SupplierGeneTex
- Product NameNBS1 (phospho Ser343) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID4683
- Target nameNBN
- Target descriptionnibrin
- Target synonymsATV; AT-V1; AT-V2; cell cycle regulatory protein p95; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); P95; p95 protein of the MRE11/RAD50 complex
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Protein IDO60934
- Protein NameNibrin
- Scientific DescriptionMutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- PI3K Inhibition Augments the Therapeutic Efficacy of a 3a-aza-Cyclopenta[alpha]indene Derivative in Lung Cancer Cells. Sanjiv K et al., 2014 Apr, Transl OncolRead more
- Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation. Moody CA et al., 2009 Oct, PLoS PathogRead more