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ICC/IF analysis of PFA fixed U2OS cells using GTX89962 nNOS antibody, C-term. Green : Primary antibody Blue : DAPI Permeabilization : 0.15% Triton Dilution : 10microg/ml
ICC/IF analysis of PFA fixed U2OS cells using GTX89962 nNOS antibody, C-term. Green : Primary antibody Blue : DAPI Permeabilization : 0.15% Triton Dilution : 10microg/ml
ICC/IF analysis of PFA fixed U2OS cells using GTX89962 nNOS antibody, C-term. Green : Primary antibody Blue : DAPI Permeabilization : 0.15% Triton Dilution : 10microg/ml

nNOS antibody, C-term

GTX89962
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetNOS1
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Overview

  • Supplier
    GeneTex
  • Product Name
    nNOS antibody, C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.50 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4842
  • Target name
    NOS1
  • Target description
    nitric oxide synthase 1
  • Target synonyms
    bNOS; constitutive NOS; IHPS1; NC-NOS; neuronal NOS; nitric oxide synthase 1 (neuronal); nitric oxide synthase, brain; nNOS; N-NOS; NOS; NOS type I; peptidyl-cysteine S-nitrosylase NOS1
  • Host
    Goat
  • Isotype
    IgG
  • Protein IDP29475
  • Protein Name
    Nitric oxide synthase, brain
  • Scientific Description
    The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5 UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Kaurenoic Acid Reduces Ongoing Chronic Constriction Injury-Induced Neuropathic Pain: Nitric Oxide Silencing of Dorsal Root Ganglia Neurons.
    Read more
  • Human resident gut microbe Bacteroides thetaiotaomicron regulates colonic neuronal innervation and neurogenic function. Aktar R et al., 2020 Nov 1, Gut Microbes
    Read more
  • Mu and Delta Opioid Receptors Are Coexpressed and Functionally Interact in the Enteric Nervous System of the Mouse Colon. DiCello JJ et al., 2020, Cell Mol Gastroenterol Hepatol
    Read more
  • Clathrin and GRK2/3 inhibitors block delta-opioid receptor internalization in myenteric neurons and inhibit neuromuscular transmission in the mouse colon. DiCello JJ et al., 2019 Aug 1, Am J Physiol Gastrointest Liver Physiol
    Read more
  • Agonist-dependent development of delta opioid receptor tolerance in the colon. DiCello JJ et al., 2019 Aug, Cell Mol Life Sci
    Read more