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FACS (Intracellular staining) analysis of A549 cells using GTX30626 NQO1 antibody [A180]. Filled histogram : primary antibody Open histogram : isotype control
FACS (Intracellular staining) analysis of A549 cells using GTX30626 NQO1 antibody [A180]. Filled histogram : primary antibody Open histogram : isotype control
FACS (Intracellular staining) analysis of A549 cells using GTX30626 NQO1 antibody [A180]. Filled histogram : primary antibody Open histogram : isotype control

NQO1 antibody [A180]

GTX30626
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Human, Mouse, Primate, Rat
TargetNQO1
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Overview

  • Supplier
    GeneTex
  • Product Name
    NQO1 antibody [A180]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Does not cross-react with NQO2.
  • Application Supplier Note
    WB: 1:1000. ICC/IF: 1:50. IHC-P: 1:100. IHC-Fr: 1:100. FACS: 1 - 2 microg/mL. IP: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    A180
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1728
  • Target name
    NQO1
  • Target description
    NAD(P)H quinone dehydrogenase 1
  • Target synonyms
    azoreductase; DHQU; DIA4; diaphorase (NADH/NADPH) (cytochrome b-5 reductase); diaphorase-4; dioxin-inducible 1; DTD; DT-diaphorase; menadione reductase; NAD(P)H dehydrogenase [quinone] 1; NAD(P)H dehydrogenase, quinone 1; NAD(P)H:menadione oxidoreductase 1; NAD(P)H:Quinone acceptor oxidoreductase type 1; NAD(P)H:quinone oxidoreductase 1; NAD(P)H:quinone oxireductase; NMOR1; NMORI; phylloquinone reductase; QR1; quinone reductase 1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP15559
  • Protein Name
    NAD(P)H dehydrogenase [quinone] 1
  • Scientific Description
    This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This proteins enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimers disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
  • Reactivity
    Canine, Human, Mouse, Primate, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Sesamin Enhances Nrf2-Mediated Protective Defense against Oxidative Stress and Inflammation in Colitis via AKT and ERK Activation. Bai X et al., 2019, Oxid Med Cell Longev
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