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NRF1 Polyclonal Antibody

RD83357A
Reddot Biotech
ApplicationsImmunoFluorescence
Product group Antibodies
TargetNRF1
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    NRF1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4899
  • Target name
    NRF1
  • Target description
    nuclear respiratory factor 1
  • Target synonyms
    alpha palindromic-binding protein; ALPHA-PAL; nuclear respiratory factor 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for nuclear factor (erythroid-derived 2)-like 1 which has an official symbol of NFE2L1.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203

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Figure 2. IHC analysis of NRF1 using anti-NRF1 antibody (A01129-2). NRF1 was detected in paraffin-embedded section of human ovary cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1microg/ml rabbit anti-NRF1 Antibody (A01129-2) overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen.
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