HeLa whole cell and membrane extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with OPA1 antibody (GTX129917) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
HeLa whole cell and membrane extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with OPA1 antibody (GTX129917) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
OPA1 antibody
GTX129917
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetOPA1
Overview
- SupplierGeneTex
- Product NameOPA1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.07 mg/ml
- ConjugateUnconjugated
- Gene ID4976
- Target nameOPA1
- Target descriptionOPA1 mitochondrial dynamin like GTPase
- Target synonymsBERHS, MGM1, MTDPS14, NPG, NTG, largeG, dynamin-like GTPase OPA1, mitochondrial, dynamin-like 120 kDa protein, mitochondrial, dynamin-like guanosine triphosphatase, mitochondrial dynamin-like GTPase, optic atrophy 1 (autosomal dominant), optic atrophy protein 1
- HostRabbit
- IsotypeIgG
- Protein IDO60313
- Protein NameDynamin-like GTPase OPA1, mitochondrial
- Scientific DescriptionThis gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Su WP, Li CJ, Lin LT, et al. Boosting mitochondrial function and metabolism in aging female germ cells with dual ROCK/ROS inhibition. Biomed Pharmacother. 2023,163:114888. doi: 10.1016/j.biopha.2023.114888Read this paper
- Ren B, Zhang T, Guo Q, et al. Nrf2 Deficiency Attenuates Testosterone Efficiency in Ameliorating Mitochondrial Function of the Substantia Nigra in Aged Male Mice. Oxid Med Cell Longev. 2022,2022:3644318. doi: 10.1155/2022/3644318Read this paper
- Li CJ, Lin LT, Tsai HW, et al. Phosphoglycerate mutase family member 5 maintains oocyte quality via mitochondrial dynamic rearrangement during aging. Aging Cell. 2022,21(2):e13546. doi: 10.1111/acel.13546Read this paper
- Yan H, Zhao H, Kang Y, et al. Parecoxib alleviates the motor behavioral decline of aged rats by ameliorating mitochondrial dysfunction in the substantia nigra via COX-2/PGE2 pathway inhibition. Neuropharmacology. 2021,194:108627. doi: 10.1016/j.neuropharm.2021.108627Read this paper
- Bijland S, Thomson G, Euston M, et al. An in vitro model for studying CNS white matter: functional properties and experimental approaches. F1000Res. 2019,8:117. doi: 10.12688/f1000research.16802.1Read this paper
- Wu LH, Chang HC, Ting PC, et al. Laminar shear stress promotes mitochondrial homeostasis in endothelial cells. J Cell Physiol. 2018,233(6):5058-5069. doi: 10.1002/jcp.26375Read this paper
Datasheet
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