OPA1 antibody
GTX129917
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetOPA1
Overview
- SupplierGeneTex
- Product NameOPA1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.07 mg/ml
- ConjugateUnconjugated
- Gene ID4976
- Target nameOPA1
- Target descriptionOPA1 mitochondrial dynamin like GTPase
- Target synonymsBERHS; dynamin-like 120 kDa protein, mitochondrial; dynamin-like guanosine triphosphatase; largeG; MGM1; mitochondrial dynamin-like GTPase; MTDPS14; NPG; NTG; optic atrophy 1 (autosomal dominant); optic atrophy protein 1
- HostRabbit
- IsotypeIgG
- Protein IDO60313
- Protein NameDynamin-like 120 kDa protein, mitochondrial
- Scientific DescriptionThis gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Boosting mitochondrial function and metabolism in aging female germ cells with dual ROCK/ROS inhibition.Read more
- Nrf2 Deficiency Attenuates Testosterone Efficiency in Ameliorating Mitochondrial Function of the Substantia Nigra in Aged Male Mice. Ren B et al., 2022, Oxid Med Cell LongevRead more
- Phosphoglycerate mutase family member 5 maintains oocyte quality via mitochondrial dynamic rearrangement during aging. Li CJ et al., 2022 Feb, Aging CellRead more
- Parecoxib alleviates the motor behavioral decline of aged rats by ameliorating mitochondrial dysfunction in the substantia nigra via COX-2/PGE2 pathway inhibition. Yan H et al., 2021 Aug 15, NeuropharmacologyRead more
- An in vitro model for studying CNS white matter: functional properties and experimental approaches. Bijland S et al., 2019, F1000ResRead more
- Laminar shear stress promotes mitochondrial homeostasis in endothelial cells. Wu LH et al., 2018 Jun, J Cell PhysiolRead more